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The Wheeler Lab

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Selected Publications

Droplet-based forward genetic screening of astrocyte–microglia cross-talk

*Wheeler, *Clark, *Lee et al., Science (2023).

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Multiple sclerosis: Neuroimmune crosstalk and therapeutic targeting

*Charabati, *Wheeler, Weiner, Quintana, Cell (2023).

Identification of astrocyte regulators by nucleic acid cytometry

*Clark, *Wheeler, et al., Nature (2023).

AstrocytePathways

Function and therapeutic value of astrocytes in neurological diseases

*Lee, *Wheeler, Quintana. Nature Reviews Drug Discovery 2022.

RABID-seq

Barcoded viral tracing of single-cell interactions in central nervous system inflammation

*Clark, *Gutierrez-Vazquez, *Wheeler, et al., Science 2021.

MicrogliaPathways

Microglia and Central Nervous System–Associated Macrophages—From Origin to Disease Modulation

*Prinz, *Masuda, *Wheeler, *Quintana. Annual Review of Immunology 2021.

Meninges

Gut-licensed IFNγ+ NK cells drive LAMP1+TRAIL+ anti-inflammatory astrocytes

*Sanmarco, *Wheeler, et al., Nature 2021.

AstrocyteEpigenetics

Astrocyte Crosstalk in CNS Inflammation

Linnerbauer, Wheeler, Quintana. Neuron 2020.

BioinformaticRegulators

MAFG-driven astrocytes promote CNS inflammation

Wheeler et al., Nature 2020.

ExposomeModel

Environmental Control of Astrocyte Pathogenic Activities in CNS Inflammation

Wheeler et al., Cell 2019.

For additional publications from the lab, see links below

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